How is hATTR amyloidosis passed down?

Hereditary ATTR (hATTR) amyloidosis is an autosomal dominant condition—meaning each child of one parent with hATTR amyloidosis has a 50% chance of inheriting a genetic mutation that causes the condition.

How hATTR amyloidosis is inherited

hATTR Amyloidosis Pedigree Chart
hATTR Amyloidosis Pedigree Chart

A family member may inherit the TTR gene mutation but having the mutation does not necessarily mean that he or she will develop hATTR amyloidosis.

Download our Family health tree tool, which can help you keep track of your family history and have a productive conversation with your doctor.

“Always remember that you are coming from a place of care and concern for your family member.”

Tootie Bueser, Cardiac Genetic Nurse
Hear a Cardiac Genetic Nurse's Advice for Talking to Your Family About Your Diagnosis

Hear about Philip and his family's experience with genetic testing for hATTR amyloidosis

Watch Philip's hATTR Amyloidosis Story